Imaging Cortical Dynamics at High Spatial and Temporal Resolution with Novel Blue Voltage-Sensitive Dyes
نویسندگان
چکیده
منابع مشابه
Imaging Cortical Dynamics at High Neurotechnique Spatial and Temporal Resolution with Novel Blue Voltage-Sensitive Dyes
vivo imaging, because it is much smaller than other Conventional imaging techniques have provided highintrinsic signals. Therefore, it has proven difficult to siresolution imaging either in the spatial domain or in the multaneously monitor the details of both the “where” temporal domain. Optical imaging utilizing voltageand the “when” aspects of neuronal information prosensitive dyes has long h...
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Conventional imaging techniques have provided high-resolution imaging either in the spatial domain or in the temporal domain. Optical imaging utilizing voltage-sensitive dyes has long had the unrealized potential to achieve high resolution in both domains simultaneously, providing subcolumnar spatial detail with millisecond precision. Here, we present a series of developments in voltage-sensiti...
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We describe the characteristics of low-cost ultra-high-power light emitting diodes (LEDs) for use in optical imaging experiments. We use the LEDs in experiments with bullfrog cardiac tissue and find that the signal-to-noise ratio is comparable to other commonly used illumination sources. Contact Information: Duke University, Department of Physics, Box 90305, Durham, NC, 27708 Tel: (919) 660-251...
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ژورنال
عنوان ژورنال: Neuron
سال: 1999
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)81027-2